Michael McConnell, Ph.D.

  • Professor Emeritus of Biology
  • Phone: 619.849.2304

Education

  • B.A., Pasadena College
  • Ph.D., Tufts University
  • Post-Doctoral: Harvard University

Background

Visiting Scholar

The Scripps Research Institute, Department of Molecular Biology, La Jolla, CA.
Laboratory of Dr. Jack Johnson
Research on virus structure (2008-present)

The Scripps Research Institute, Department of Molecular Biology, La Jolla, CA.
Laboratory of Dr. Gerald Joyce
Research on molecular evolution of ribozymes (1994)

University of Sydney, Department of Microbiology, New South Wales, Australia
Laboratory of Dr. Peter Reeves
Research on bacteriophage-encoded gene products that cause structural modification of lipopolysaccharides in Group E1 salmonellae bacterium (1994)

UCSD Department of Biology, San Diego, CA
Laboratory of Dr. Masaki Hayashi
Research on factors influencing messenger RNA stability (1985-1986)

UCSD Medical Center, San Diego, CA
Laboratory of Dr. Ivor Royston
Research on monoclonal antibodies to immunoglobulin idiotypic antigens (1983)

COURSES TAUGHT

Advanced Biochemistry
Molecular Biology

Research

Virus/host cell surface interactions. Dr. McConnell studies Epsilon 15 and other bacteriophages that infect Group E1 Salmonellae bacteria. He uses genetic and biochemical approaches to analyze the interactions that occur between the tail protein of the virus and the lipopolysaccharide that is in the cell wall of the bacterium during the initial infection process. He is also interested in the mechanism, used by these phages, to modify the lipopolysaccharide structure of their Salmonella host cell shortly after infection, a phenomenon known as "cell surface conversion".  Over the years, Dr. McConnell's research has been funded by the National Institutes of Health, the Cystic Fibrosis Foundation, the National Science Foundation and Research Corporation.

Summer Research

Interests

Celebrating 50 Years of Science and Math
American Scientific Affiliation (ASA) Meeting
Perspectives on Science
Research Associates
West Coast Biological Sciences Undergraduate Research (WCBSUR) Conference
Check out Dr. McConnell's funny science building video